Not sure what language you are using, but this is how i tend to do it in PHP:
$count = $client->call("GET", "/admin/products/count.json");
if ($count > 0) {
$pages = ceil($count / 250);
for ($i=0; $i<$pages; $i++) {
$products = $client->call("GET", "/admin/products.json?limit=250&&page=".($i+1));
foreach ($products as $product) {
// your processing here
}
}
}